![]() ĭofetilide is indicated in adults for the conversion of atrial fibrillation or atrial flutter to normal sinus rhythm (NSR) and the preservation of normal sinus rhythm in patients with highly symptomatic atrial fibrillation or atrial flutter of more than one week whose pathological sinus rhythm has converted to normal. In the DIAMOND studies (Torp-Pedersen C et al., 1999), dofetilide did not affect mortality in patients with advanced heart failure or those convalescing from acute myocardial infarction. ĭofetilide is effective in maintaining sinus rhythm in patients with atrial fibrillation. The formula also contains inactive ingredients of microcrystalline cellulose, corn starch, colloidal silicon dioxide, magnesium stearate, gelatin, titanium dioxide, and FDC Yellow 6. So this is just another piece of the puzzle that tells us that as our technology gets better, as we become better at managing AFib and treating AFib, that we work harder in trying to fix AFib,” he added.It is an oral medication containing dofetilide as the active ingredient. “People with AFib tend in general to not live as long as people who don’t have AFib. “I think most of us in the field that manage atrial fibrillation recognize all the potential bad outcomes that can come from atrial fibrillation, the majority of which involves having a stroke, having congestive heart failure,” he continued. Doshi said additional research should include the classification of different types of dementia and have a way to ensure people who are in the none-AFib category do not actually have undiagnosed AFib. In some patients, it seems to be okay, but is it potentially that you’re not getting as much blood flow to the brain? And over 100,000 heartbeats a day, day after day, year after year, does that accelerate someone having dementia?”ĭr. “There’s also a theory that in atrial fibrillation, your heart doesn’t squeeze as well as it does with normal rhythm in many patients. We know patients with atrial fibrillation have a higher risk of stroke, and (they) could be having small mini-strokes, which can lead to vascular dementia,” Dr. ![]() “There’s a lot of proposed hypotheses on how this could happen. He said we do not know yet how AFib might heighten a person’s dementia risk. Shephal Doshi, a cardiac electrophysiologist and director of cardiac electrophysiology and pacing at Providence Saint John’s Health Center in Santa Monica, California, about this study. We did not find differences by sex, race, or ethnicity.” “The findings in the subgroups were of particular interest - we found that the association of atrial fibrillation with risk of dementia was stronger in patients who were younger and those without kidney disease. “With this approach, we were not surprised to find this somewhat modest association between incident atrial fibrillation and risk of dementia,” Dr. And people without chronic kidney disease had a 14% higher risk for dementia than those with the condition. Bansal and her team found adults under the age of 65 had a 65% higher dementia risk compared to adults 65 and older. All told, people with AFib had a 13% higher risk of developing dementia.Īdditionally, Dr. Upon analysis, scientists found an average of 2.79 diagnoses of dementia occurred among 100 people over one year with AFib, compared to 2.04 diagnoses in people without over the same time period. In this study, researchers analyzed health data from almost 200,000 adults in California. We designed the present study to try to address some of the limitations of prior studies,” Dr. “Previous studies on the association of atrial fibrillation with dementia have yielded conflicting results, with some studies reporting a strong association and others demonstrating no association. “Biologically it seems plausible that atrial fibrillation may be linked with other important neurological complications, even in the absence of strokes, which motivated this study,” she told Medical News Today. Nisha Bansal, a professor and the Arthur Stach Family Endowed Professor in the Division of Nephrology at the University of Washington School of Medicine and corresponding author of this study, it is well known that atrial fibrillation may lead to strokes, yet associations with other complications are less recognized.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |